Cancer stem cells in oncology.
نویسندگان
چکیده
Cancer stem cells (CSCs) possess several characteristics including self-renewal, pluripotency and tumorigenicity and constitute a rare population in a tumor mass. Because conventional cancer therapies can not kill CSCs, these cells are responsible for tumor relapse and metastasis. Currently, with advances in the identification of CSCs, the importance of these cells is increasing in the field of cancer diagnosis and prognosis. In addition, clarifying the mechanisms responsible for the maintenance of CSCs properties led to the development of CSC-targeted therapies.
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عنوان ژورنال:
- Journal of B.U.ON. : official journal of the Balkan Union of Oncology
دوره 17 4 شماره
صفحات -
تاریخ انتشار 2012